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control FoB ( Gclc fl/fl Mb1-cre + FoB vs
A 2012 Cochrane Review of pooled data from three trials examining tracheostomy-free survival in 974 patients treated with riluzole and 503 placebo-treated patients demonstrated a statistically significant increase in survival from 11.8 months to 14.8 months, but without any benefit on measures of muscle strength
Jan 2013;22(1):173-175
Intermembrane proteins released from mitochondria through Bax/Bid pores, e.g., apoptosis inducing factor (AIF) and endonuclease G, translocate to the nucleus and cause DNA fragmentation [53]
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