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(11,12) Thymosin beta-4 is thought to influence cellular functions through interactions with ATP synthase enzymes on the cell surface, which play a key role in energy production

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According to recent statistical data among all COVID-19 patients, ~19% of them were severe or critical, most of which displayed remarkably increased serum levels of pro-inflammatory cytokines and subsets of immune cells ( The Immune Response and CRS in COVID-19 Recent advances in the pathophysiologic understanding of COVID-19 suggests that CRS has a great association with the severity of disease due to increased serum levels of tumor necrosis factor (TNF-), granulocyte-colony stimulating factor (G-CSF), interferon gamma-induced protein 10 (IP-10), monocyte chemoattractant protein 1 (MCP-1) and macrophage inflammatory protein 1 (MIP1A) ( Initial reports have also determined that a multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 may cause public concern