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Glutathione depletion causes a JNK and p38 MAPK -mediated increase in expression of cystathionine--lyase and upregulation of the transsulfuration pathway in C6 glioma cells

Application to authentic plasma samples The analytical approach has been applied for the determination of Cys, Hcy, GSH and N-Hcy-Lys in plasma samples collected from five apparently healthy volunteers in the age range 3245 years

as a small molecule which could kill cancer cells possessing the RAS and small T oncogenes, induces oxidative, iron-dependent cell death by inhibiting xCT and subsequently depleting GSH [28]

Singh et al., 1993