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From ultrasoft pseudopotentials to the projector augmented-wave method

As such, the association with efficacy may be the result of enhanced trafficking of the protein within the cell that ultimately modulates the cell surface abundance of the receptor, rather than the result of alterations in the receptor protein structure that may influence ligand affinity

Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, et al

In chronic stages like advanced fibrosis or cirrhosis, D1 activity decreases while type 3 deiodinase activity increases, leading to enhanced degradation of T3 and T4 into inactive metabolites such as reverse T3 (rT3)

Differentiating between white and grey matter, allowed for a more precise understanding of the diseases impact on different brain regions