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It has been studied extensively in the context of energy metabolism, exercise physiology, and cardiac biology

10.1016/j.bcp.2016.09.023 12

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The current guidelines for the treatment of acute coronary syndrome and secondary prevention recommend medications such as inhibitor of platelet activation and aggregation, lipid modification drugs, -blockers, and inhibitors of the renin-angiotensin-aldosterone system (RAAS) (Roffi et al., 2016

The clinical study GeneBank was supported in part by P01 HL076491, P01 HL098055, R01 HL103931 and the Cleveland Clinic Foundation General Clinical Research Center of the Cleveland Clinic/Case Western Reserve University CTSA (1UL1RR024989)