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The expression of HSPA5 was reported to be higher in high-risk endometrial cancer than in low-risk endometrial cancer and normal endometrium, which suggested that HSPA5 was also associated with higher malignant degree and poor prognosis of endometrial cancer (Teng et al., 2013)
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Since DFO is membrane impermeable and accumulates in lysosomes 18 , we believe that it protects the cells against ferroptosis by chelating lysosomal iron as described previously 47
Kinetics and stoichiometry of fatty acid peroxidation
The intermediate metabolites of glutamine can enter the TCA cycle, thus ensuring the replenishment of the TCA cycle under the condition of glucose deficiency
