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for example, some bacteria may produce SCFAs that have anti-inflammatory effects, while others may produce substances that increase inflammation and contribute to the development of hypertension (130)

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doi: 10.1123/ijsnem.10.2.199

Noteworthy, the administration of DHA (daily doses of 300 mg/kg) combined with T3 (0.05 mg/kg) to rats increased significantly the content of RVD1 and RVD2 in the liver, but left unchanged that of RVE1 and RVE2, indicating a synergistic effect compared to treatment with DHA alone and T3 alone ( Omega-3 PUFA-Based Nutraceuticals in the Setting of Thyroid Disorders: Experimental Setting Experimental studies that have evaluated the thyroidal effects of the omega-3 PUFA (137143) are summarized in Table 5