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Description
Schildberg FA, Hegenbarth SI, Schumak B, Scholz K, Limmer A, Knolle PA
A previous study indicated that GCH1 prevents ferroptosis via its metabolites, tetrahydrobiopterin (BH4) and dihydrobiopterin (BH2)
Further doseresponse and steady-state administration studies will be required to optimize the dosing schedule for future trials to evaluate therapeutic efficacy
No formal half-life measurement has been published
This sequence merges a segment of adrenocorticotropic hormone (ACTH, specifically ACTH 4-7, or Met-Glu-His-Phe) with a Pro-Gly-Pro extension at the C-terminus
