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Floyd ZE, Wang ZQ, Kilroy G, Cefalu WT

The BBB regulates the microenvironment through its ion channels and transport proteins, maintaining the ion homeostasis and nutrients required by the brain

Interleukin-12/23 Inhibitors Ustekinumab (UST) is the only anti-interleukin (IL)-12/IL-23 approved for UC at this time, and acts by binding to the p40 subunit of IL-12 and IL-23, preventing the interaction of these cytokines with the IL-12 receptor 1 subunit of the IL-12 and IL-23 receptor complexes, thus affecting lymphocytes' function and downregulating proinflammatory cytokines

Clock gene expression in adult primate suprachiasmatic nuclei and adrenal: is the adrenal a peripheral clock responsive to melatonin

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