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Glutathione (GSH), a combination of three amino acids made by the body, had become a fad for skin bleaching

Its pharmacological precursor, ethyl pyruvate, has shown anti-inflammatory/anti-tissue injury effects in various animal models of disease, but failed in a multicenter clinical trial

Glutathione is a well researched antioxidant that plays an important role in healthy detoxification processes, protecting cells from free radical damage, maintaining cellular health and supporting overall immune function

Collectively, our findings reveal that KRT14 contributes to chemoresistance in BLCA not only via its structural roles but also by directly regulating translational machinery through eIF4H, leading to upregulation of the metabolic enzyme ACOX2

Glutathione may be depleted by chronic inflammation, ongoing immune activation, elevated toxic body burden, and high levels of oxidative damage