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Detection and quantification of S-nitrosoglutathione (GSNO) in pepper ( Capsicum annuum L.) plant organs by LC-ES/MS

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10.1126/scitranslmed.3007154 191 MacielagM

Accordingly, we systematically summarize innovative strategies that offer new therapeutic possibilities, including targeting multiple metabolic pathways through combination therapy to enhance efficacy, combining metabolic inhibitors to overcome resistance to conventional anticancer agents, leveraging metabolic reprogramming for early cancer detection, and exploring emerging approaches such as immunometabolism and metabolomics

The study was conducted using a rat model of migraine induced by nitro-glycerine