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Chemical proteomic profiling of human methyltransferases

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Alterations of this current production of peroxides and free radicals damage structural components of the cell

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Testosterone supplementation partially repaired oxidative damage in ventral prostate epithelia of castrated rats receiving testosterone replacement therapy had a partial decrease in NAD(P)H oxidase expression but an increase in GPx1, SOD2, peroxiredoxin 5 expression, thioredoxin, CAT, glutathione reductase (GR), c-glutamyl transpeptidase, and glutathione synthetase expression in the regenerating ventral prostate tissue