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Excessive release of glutamate and its binding with NMDA, -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), or kainite (KA) receptors promotes excitotoxicity cell injury with a consequent activation of many molecular pathways, resulting in intracellular calcium (Ca 2+ ) overload 90,91 , reactive oxygen species (ROS) production, mPT, and cell swelling with brain edema 92

What consistently holds across interventions: patients who understand their own metabolic profile before they start are the ones who respond best and who can tell whether what they are doing is actually working

Through bulked segregant analysis (BSA), researchers mapped 20 SSR markers linked to rhizome traits in 8 genomic regions, including 5 novel loci, and selected elite lines with high rhizome biomass, biomass yield, and grain yield (Zheng et al., 2025)

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