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Expert Opin Ther Pat 28:197210 Cioffi CL, Wolf MA, Guzzo PR, Sadalapure K, Parthasarathy V, Dethe D, Maeng J-H, Carulli E, Loong DT, Fang X (2013) Design, synthesis, and SAR of N-((1-(4-(propylsulfonyl) piperazin-1-yl) cycloalkyl) methyl) benzamide inhibitors of glycine transporter-1

The flow cytometry results indicated that the crude extract of PL316 fermentation broth induced apoptosis in MGC-803 cells, and the death rate gradually increased as the treatment time extended (Fig
doi:10.1523/JNEUROSCI.4770-06.2007

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The capacity of quercetin to form hydrogen bonds and engage in - stacking interactions enables it to modulate, mainly inhibiting, the activity of enzymes like cyclooxygenase (COX), lipoxygenase (LOX), and kinases, impacting inflammatory and cell signaling pathways involved in cancer
