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This process is a crucial prerequisite for GSH biosynthesis and also an important molecular switch for ferroptosis initiation ( 2 ) ( Intracellular cystine is reduced to cysteine, the key precursor for GSH synthesis, while NADPH from the pentose phosphate pathway supplies reducing equivalents for this antioxidant system

(August 2001)

Endocrinology 148, 310316 (2007)

Diagnosis of nephrogenic systemic fibrosis by means of elemental bioimaging and speciation analysis

(3) Organ-centric reductionism: the current investigations predominantly focus on isolated organ systems, neglecting BBRs pleiotropic effects within inter-organ communication networks critical to systemic metabolic regulation