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J Am Med Dir Assoc 2023;24(6):827832

The action of the hydroxyl free radical on cardiolipin releases 4-hydroxynonenal (4-HNE) and on other mitochondrial lipids and mtDNA releases malondialdehyde (MDA), acrolein, and crotonaldehyde

Vitamin 1000 mcg of B12 Safe

8,9 Table 1 Risk Factors for Vitamin B12 Deficiency A multicenter randomized controlled trial of 390 patients with diabetes mellitus showed that those taking 850 mg of metformin three times per day had an increased risk of vitamin B 12 deficiency (number needed to harm = 14 per 4.3 years) and low vitamin B 12 levels (number needed to harm = 9 per 4.3 years) vs

A 5mg/mL concentration becomes 5,000mcg/mL