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Injecting in a fasted state (12+ hours post-meal, typically upon waking) maximizes the NAD+-to-fat-oxidation pathway because insulin is low, glucagon is elevated, and free fatty acids are already mobilized from adipose tissue

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2014;37(2):e22-23

As with anything healthcare-related, it should be learnt from a professional

4 Discussion This systematic review and meta-analysis provide a comparative evaluation of oral, sublingual, and intramuscular (IM) vitamin B12 supplementation in the management of B12 deficiency
