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A.KulkeM
Each IGFBP can bind to IGF-1 with high affinity and is regulated by several specific IGBPB proteases

These substances must undergo biotransformation to become water-soluble for excretion

Minerva Ginecologica , 2005, 57:619-25

MartinotAJFarrowMBaiLLayreEChengTYTsaiJHet al
