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Research indicates that oral L-citrulline supplementation produces more efficient nitric oxide synthesis by bypassing first-pass hepatic metabolism that typically degrades L-arginine before it can reach target tissues [2]

[DOI] [PMC free article] [PubMed] [Google Scholar] 210.Kang D.W., Adams J.B., Coleman D.M., Pollard E.L., Maldonado J., McDonough-Means S., Caporaso J.G., Krajmalnik-Brown R

These experiments use light generating molecules that either bind to one of the protein tags, such as the fluorophore-labeled antibody in Figure 3

Scientists can also make synthetic peptides in the lab

Wei Z, Li X, Li X et al (2018) Oxidative stress in Parkinsons disease: a systematic review and meta-analysis