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Native GLP-1 provides transient, meal-related metabolic effects lasting minutes, contributing to normal postprandial glucose regulation but offering no sustained therapeutic impact

HGF treatment supports the formation of functional synapses as indicated by a high correlation between postsynaptic spines (red) and markers of presynaptic active zones (green)

Mfn2, a mitochondrial fusion protein, is phosphorylated by PINK1, which promotes the recruitment of Parkin to the outer mitochondrial membrane and initiates Parkin-dependent mitophagy (Twig et al., 2008)