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But the gap between those results, the side effect profiles, the costs, and the long-term sustainability of each approach has grown so wide that choosing the wrong one for your situation could mean years of frustration
2024), our data indicate that the K58 delactylation effect is independent of lactate release or pyruvate flux, but rather operates through the STAT1/SLC7A11 axis

doi: 10.1001/jamanetworkopen.2025.17268, 77
doi: 10.1016/j.jconrel.2011.10.023

Unfortunately, despite its high prevalence, a large number of MASLD cases remain undiagnosed, often leading to a diagnosis of cryptogenic cirrhosis, where MASH is the underlying condition once other etiological factors for chronic liver disease, such as alcohol abuse, viral hepatitis, autoimmune disorders, and other metabolic diseases, have been excluded [23]