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Mak PY, Maiti A, Tomczyk T, Cottens S, Walczak M, Andreeff M , Carter B

Hydrogen peroxide acts as a secondary messenger in signal transduction due to its relatively long half-life and ability to diffuse through the aquaporin channels in the membrane followed by the Fenton reaction in the presence of transient metal ions (Fe 2+ , Cu 2+ , Co 2+ ) resulting in the production of highly reactive hydroxyl radicals

If free radicals are left unchecked, the resulting oxidative stress can lead to: Adequate levels of glutathione can prevent this kind of oxidative stress by neutralizing free radicals

It has been used to prepare a standard curve for GSH analyses