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Common side effects are usually mild and temporary
As mentioned previously, mast cells and keratinocytes can induce vascularization through the increment in VEGF secretion, enhanced TGF- and FGF-2, thus can create more, larger, and highly dilated vessels which are considered important targets in melasma treatment (Kim et al., 2005
This is especially helpful in the UK, where getting NHS testing can sometimes involve a wait
PMID: 3189960 Rahman I
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