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The reasoning is flawed because we now know that increasing mash hop additions of high-precursor cultivars can lead to highly detrimental effects to the overall beer quality

The Nrf2 antioxidant defense pathway might therefore provide a therapeutic target for ameliorating OS associated with adverse pregnancies and could provide an opportunity to modulate developmental priming via OS
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Oncogene 2014;33:3267-76

doi: 10.1136/gut.39.2.262
