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Hematological assessments (CBC, comprehensive metabolic panels) have remained within normal reference ranges in chronic dosing cohorts

Interestingly, serine synthesis has been found to be inhibited upon genetic inhibition of malate-aspartate shuttle components due to a low NAD + /NADH ratio [98]

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Sun X., Yang D., Li Y., Shi J., Zhang X., Yi T