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Description
111 3-MST uses 3-MP, derived from cysteine through the action of CAT, as an activating substrate to generate a persulphide at the catalytic Cys248 residue

In addition, vestibular hair cells and supporting cells were absent (Rakowiecki and Epstein, 2013)

This variant, unlike previous GPX4 variants associated with SSMD, is compatible with survival, albeit with a developmental impact (Figure 3)
Stealth coating of nanoparticles in drug-delivery systems
Depending on the underlying cause, long-term vitamin B 12 replacement may be needed
