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4 Effect of oxidative stress on diabetic cognitive dysfunction 4.1 Overview of oxidative stress Oxidative stress is a classical biological process and refers to a redox imbalance state in which oxidants such as ROS are produced in excess with impaired antioxidant defense systems in the body (31)

If a patient does smoke on the day of surgery, it should be at least two hours before the procedure, according to the American Society of Regional Anesthesia and Pain Medicine, because smoking marijuana can significantly increase heart rate and blood pressure within the two hours following use, and it may increase the patients risk of suffering a surgery-related heart attack. It's also unclear when its safe to resume marijuana use following surgery

Others do better with once daily or even every other day long-term

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These apparent discrepancies could be attributed to differences in the expression of AGE receptors on the surface of various cell types
