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This abolishes UBE2N E2 activity in forming K63-type polyubiquitin chains and dampens the activation of the Nuclear factor-B (NF-B) (Puvar et al., 2020) ( Figure 1B ), a key regulator of the macrophage M1 polarization ( Legionella persisters, similarly to those produced by S

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doi: 10.1016/j.phymed.2022.154524 [DOI] [PubMed] [Google Scholar] 38.Kakran M, Shegokar R, Sahoo NG, et al