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Elevated FSP1 expression partially reverses sorafenib-induced ferroptosis, whereas FSP1 inhibition enhances HCC cell sensitivity to sorafenib-induced ferroptosis (106)

(2012) 129(2):45663, 63.e13

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Acid sphingomyelinase promotes mitochondrial dysfunction due to glutamate-induced regulated necrosis

Academic research provides the foundational understanding of cellular senescence and aging, while industry partners have the resources and expertise to translate this knowledge into viable therapies.126 Regulatory bodies, such as the FDA, will play a critical role in establishing guidelines for the safe and effective use of these therapies in clinical practice