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Insulin resistance: STAT3/SOCS signaling suppresses insulin/IGF-1 pathway The signaling pathways of several cytokines and growth factors, such as insulin/IGF-1, converges at the activation of STAT3 factor (Figs

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The released Mn 2+ can in turn mediate Fenton-like reactions by catalyzing the generation of highly active OH from H 2 O 2 (32) to induce high oxidative stress in tumor cells and the production of proinflammatory factors, such as TNF- (5255)

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[DOI] [PMC free article] [PubMed] [Google Scholar] Rasheed A., Azeez F.A., R

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