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Description
Pigmented dark circles stem from melanin accumulation in periorbital skin from chronic sun exposure without adequate protection, post-inflammatory hyperpigmentation from rubbing or allergies, genetic predisposition particularly in darker skin types, or hormonal influences affecting melanocyte activity

At 1 mg weekly, participants lost modest amounts

What conversation are we supposed to have with patients

doi: 10.1016/j.phrs.2020.105143 384 WangX.RyuD.HoutkooperR

Its unique mechanism of action does not interfere with hormone-related peptides or tissue repair compounds
