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The tissue injury associated with OTA was accompanied by a disruption of pathways related to the transcription factors hepatocyte nuclear factor 4 alpha (HNF4) and nuclear factor-erythroid 2-related factor 2 (Nrf2) [73]

doi: 10.4049/jimmunol.179.10.7079
Thinking of it in those terms will only lead to confusion and misplaced expectations

Dev Dyn 218: 213-234

Source: Purality Health