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10.3233/JAD-2010-1239 336 SoJ
SIRT1 deacetylates histones and transcription factors like p53 and NF-B to regulate gene expression
doi: 10.1016/j.clinbiochem.2008.02.001
& Dolores Dor Eccles Professor of Ophthalmology & Neuroscience, Wilmer Eye Institute, The Johns Hopkins School of Medicine involving oxidative stress in the retina provided impetus for exploring small molecule antioxidant therapies
The beneficial effect exerted by IGF-I on I/R injury is consistent with previous findings that IGF-I accelerates muscle regeneration by modulating inflammatory cytokines[67]
