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the invention provides an antibody that specifically binds to an EphA2 polypeptide, said antibody encoded by a nucleotide sequence that is at least 65%, preferably at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, or at least 99% identical to the nucleotide sequence encoding 2B12

doi: 10.3389/fmicb.2015.00187

Translationality is reinforced by animal work, which has shown that oral or parenteral delivery of phytochemicals has the ability to inhibit PI3K/Akt/mTOR signals in tumor xenografts, genetically engineered tumor models and inflammatory disease models

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On the basis of AMES toxicity, hERG inhibition, hepatotoxicity, and cutaneous sensitization, the toxicity of drugs is predicted