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In the first phase, an enzyme will oxidize a portion of the toxin in order to make it more reactive and prepare it for the second phase
10.1111/exd.70005 23 GuY.HanJ.JiangC.ZhangY
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Cell Biochem 424 (1), 185193
The reason is that, for receptor agonism and allosterism, the maximal response can be less than the maximal system response if partial agonism, strong negative allosterism or weak positive allosterism is involved
