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Specifically, M1-type macrophages are associated with pro-inflammatory reactions, while M2-type macrophages are known for their anti-inflammatory properties and involvement in tissue repair

Ruthenium-catalyzed azidethioalkyne cycloadditions in aqueous media: a mild, orthogonal, and biocompatible chemical ligation

Gupta J, Gill HS, Andrews SN, Prausnitz MR

At standard human doses (1 to 2 mg per day for a 70 kg person, or 0.014 to 0.028 mg/kg), copper toxicity risk is negligible
