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Effects of cyclic strain on endothelial cell apoptosis and tubulogenesis are dependent on ROS production via NAD(P)H subunit p22phox
However, 70 nm is reported lethal at 45 mg kg 1 , and 30 nm is lethal at 12 mg kg 1 in mice
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Indeed, Perez-Mana et al
Zhang T., Li S., Wang L., et al., Design, Synthesis and Biological Evaluation of N(4Alkoxy3Cyanophenyl)Isonicotinamide/Nicotinamide Derivatives as Novel Xanthine Oxidase Inhibitors, European Journal of Medicinal Chemistry 141 (2017): 362372, 10.1016/j.ejmech.2017.09.051
