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When autoimmune responses to CII and oxPTM-CII were analyzed according to HLA-DRB1 subtypes, we found that ROS-CII but not native CII autoimmunity was restricted to the HLA Shared Epitope (SE) containing DRB1*04 alleles (112), known to confer the greatest risk for developing RA (OR 3-13) (113)

Microtubules acquire resistance from mechanical breakage through intralumenal acetylation

These findings are consistent with those from a different study (Wancket et al., 2012), in which rats fed a diet rich in cocoa displayed raised basal levels of the MAPK phosphatases MKP-1 and MKP-3, preventing the cerebral peripheral flogosis caused by MAPK

In many cases the GT levels are higher in the corresponding primary tumor (Maellaro et al., 2000)

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