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Stage II begins with the onset of liver injury, generally within 24 hours but always within 36 hours of ingestion (14)

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5.3 Cytokines and macrophage polarization Ferroptosis-driven inflammation promotes the polarization of macrophages toward an M2-like, pro-fibrotic phenotype, largely mediated by cytokines such as TGF- and IL-10 (164)

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