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GCMS measurements were performed on a combined set-up of a 7890B GC with a 5977B MSD (Agilent Technologies)

Santos LFL, Freitas RLM, Xavier SML, Saldanha GB, Freitas RM

43 In a study by Sang et al using in vitro experiments with LPS-stimulated ML-12 cells, Quercetin was found to modulate the SIRT1/AMPK pathway to inhibit both endoplasmic reticulum stress and oxidative stress levels in cells, which was manifested by a decrease in the expression of PDI, CHOP, GPC78, ATF6, PERK, and IRE1A, together with enhanced mitochondrial function, and increased levels of matrix metalloproteinase (MMP) and superoxide dismutase (SOD) while reducing the production of ROS and MDA, which in turn reduced the release of inflammatory factors in the cells

This increased cellular activity makes your skin more sensitive, more permeable, and more reactive to other ingredients

Ortega Martnez, M.E