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[74] conducted an experiment in 60 participants with normal weight or obesity and found that as factors such as BMI, obesity, blood pressure, and MetS scores worsened, the methylation levels at certain CpG sites increased

A phase 1 clinical trial in RTT patients found no adverse effects of recombinant human IGF-1 (rhIGF-1) (Khwaja et al

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Front Neurosci 2013