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In high L-arginine-dependent tumors, such as breast cancer (Abdelmagid et al., 2013), and HCC (Kishikawa et al., 2015), increased expression of the transporter CAT-1 ( SLC7A1 ) has been observed, and CAT-1 ( SLC7A1 ) knockdown decreases the viability of cancer cells and induces apoptosis

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1E), the above conclusion can also be verified

In contrast, L-serine can inhibit the growth of certain bacterial strains and enhance the efficacy of antibiotic treatment 102,103