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In this work, we develop a -glutamyl transpeptidase (GGT)-activable nanoprobe that maintains a neutral surface charge (10 mV) in the blood circulation, aiming to utilize the efficient cross of BBB via AMT-based drug delivery while avoiding the toxic side effects of cationic nanodrugs

Therapeutic strategies targeting ROS Antioxidant strategies Radical-focused strategies Traditional antioxidant strategies were fundamentally rooted in a simplistic, one-size-fits-all scavenging strategy (Tables 1 and 2)

It achieves this by controlling the expression of pluripotency genes through the regulation of GSH homeostasis and the suppression of the mesoderm-inducing protein Brachyury ( The significance of CHAC2-NRF2 signaling pathway extends beyond development

Cripps, A

It protects our DNA, cell lipids, and proteins from free radicals and oxidative stress