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In healthy individuals who received doses of curcumin ranging from 0.5 to 12 g/d, serum levels of this curcuminoid were only noticeable in volunteers who received doses higher than 4 g/d (Lao et al., 2006)
A.WhitmoreC.FreinbichlerW.WeinbergerP.TiptonK
doi: 10.3390/biomedicines12020383
Effect of a high salt diet on microvascular antioxidant enzymes

Weighing risks and benefits of liraglutide--the FDA's review of a new antidiabetic therapy