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A healthy gut microbiome (balanced community of microorganisms, including bacteria, viruses, and fungi) is believed to be essential for normal physiological activities, including the circadian rhythm and sleep (Figure 7) [168]

They found that among 46 -glutamyl peptides, glutathione (-glutamyl-cysteinyl-glycine) and -glutamyl-valinyl-glycine (-Glu-Val-Gly) were very strong calcium-sensing receptor (CaSR) agonists that increased the kokumi flavor of chicken consomm and enhanced sweet, salty, and umami tastes independently when added to aqueous solutions of sucrose, NaCl, and MSG, respectively, in human sensory tests

Vitamin B12 Vitamin B12 plays a critical role in red-blood-cell production, neurological function, and energy metabolism

Am J Physiol Endocrinol Metab 310:E388E393