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NICE guidance recommends at least 150 minutes of moderate-intensity aerobic activity per week, following a Mediterranean-style diet, reducing refined carbohydrates and added sugars, and limiting alcohol consumption in line with UK Chief Medical Officers' guidance

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Pyruvate kinase deficiency (PKD), an autosomal (chromosome 1q21) recessive genetic disorder that affects the ability of RBCs to make energy, is the cause of hemolytic anemia in different degrees (Figure 3) [73]

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