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244 A dose-dependent inhibition has been reported in acetylcholine, histamine, serotonin, and calcium-induced contraction in isolated rabbit ileum samples exposed to aqueous and ethanol extracts of Jamun fruits, whereby 3 mg/mL and 5 mg/mL extracts were more effective than 1 mg/mL and 2 mg/mL

Although antioxidant supplementation is generally safe, it does not mean that the more you consume, the better

Moreover, stress can compromise the skins natural barrier function, making it more susceptible to environmental damage and dehydration

They have the ability not only to deliver lipophilic bioactive substances that do not dissolve easily in an aqueous media and exhibit problems with their absorption and bioavailability e.g., vitamins, curcumin, etc

In the ischemia phase of I/R, induction of ALOX15 triggers oxidization of PUFA-phospholipids, especially PUFA-phosphatidyl ethanolamines (PEs) leading to cardiomyocyte ferroptosis [26, 27]