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The inhibition of mTORC1 signaling by cystine starvation demonstrated that regulation of this pathway is not limited to essential amino acids 9,10,11,12 , but is also regulated by cysteine availability (Fig
Its primary biological function is to protect cellular machinery from oxidative stress by neutralizing reactive oxygen species (ROS), such as superoxide radicals and hydrogen peroxide, which are natural but destructive byproducts of cellular energy production
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