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Li J, Liu Y, Xu H, Fu Q

Dexpramipexole attenuates myocardial ischemia/reperfusion injury through upregulation of mitophagy
6,7 Conversely, nonsurgical periodontal therapy such as scaling and root planing have demonstrated an increase in glutathione levels, suggestive of an improved antioxidant status and reduction in oxidative stress, perhaps partly due to a reduction in the proteolytic activity of bacteria and reductions in inflammation
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Moreover, it has been shown that stomach cancer is more likely to develop as a result of the oxidative stress brought on by CagA-positive bacteria (74), in which H pylori CagA produces cells with oxidative DNA damage by inducing spermine oxidase (SMO), and a portion of these cells are apoptosis-resistant and therefore highly susceptible to developing cancer (75)
