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the definition of this profile showed a good level of homogeneity (mean inter-item Spearman 0.25) [41] and has been extensively described previously as belonging to the immuno-metabolic depression (IMD) domain, based on previous findings on individual symptoms with immuno-metabolic dysregulation [2]

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[DOI] [PubMed] [Google Scholar] 42.Judd LL, Schettler PJ, Akiskal HS, et al